Emory University

Contact Info:

Kristal Maner-Smith, PhD Core Director

O. Wayne Rollins Research Center Rooms 4019, 4021 1510 Clifton Road, Atlanta, GA 30322

Atlanta, GA 30322

https://www.cores.emory.edu/eimlc/

Grants and Identifiers:

RRID: RRID:SCR_023527

Instrumentation:

Services Provided:

Relevant Publications:

1.) Rock CM, Johnson LM, Westbrook AL, Parsons R, Roback JD, Damhorst GL, Lam WA, Martin GS, Houser MC, Frediani JK (2026 Jun). Exploratory comparison of PASC and SARS-CoV-2 infection through metabolomics and lipidomics in early pandemic and Omicron-era. Biochemistry and Biophysics Reports, 46(), . . PMCID: 13241759.

2.) Lim G, Huneault HE, Chen CY, Won G, Sanchez-Torres C, Maner-Smith K, Vos MB (2026 Apr 22). Untargeted plasma lipidomic profiling associated with pediatric metabolic dysfunction-associated steatohepatitis (MASH). Lipids in health and disease, 25(1), . . PMCID: 13235174.

3.) Maner-Smith K, Chen CY, Hou Z, Gulbin XL, Ahn J, Ortlund EA, Dunlop AL, Ferranti E (2025 Nov 5). Postpartum lipid dysregulation in African American women who experienced cardiometabolic complications of pregnancy iScience, 28(12), 113955. . PMCID: 12670567.

4.) Huneault HE, Chen CY, Cohen CC, Liu X, Jarrell ZR, He Z, DeSantos KE, Welsh JA, Maner-Smith KM, Ortlund EA, Schwimmer JB, Vos MB (2024 Mar 28). Lipidome Changes Associated with a Diet-Induced Reduction in Hepatic Fat among Adolescent Boys with Metabolic Dysfunction-Associated Steatotic Liver Disease Metabolites, 14(4), 191. . PMCID: 11052520.

5.) Ortlund E, Chen CY, Maner-Smith K, Khadka M, Ahn J, Gulbin X, Ivanova A, Dammer E, Seyfried N, Bennett D, Hajjar I (2024 Feb 27). Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia Research Square, (), rs.3.rs-3973736. . PMCID: 10925467.

6.) Nayak A, Chavarria A, Sanders KN, Ghalei H, Khoshnevis S (2023 Oct 15). Sinefungin, a natural nucleoside analog of S-adenosyl methionine, impairs the pathogenicity of Candida albicans bioRxiv, (), 2023.10.12.562127. . PMCID: 10592816.

Description:

The Emory University Lipidomics Core Facility will provide quantitative lipidomics analyses on lipid samples from a wide variety of biological matrices, e.g. blood, serum, plasma, solid tissues, cell extracts, etc., to support both clinical and basic research efforts on campus. These analyses will provide insight on lipids and lipid precursors whose abundance can be monitored as biomarkers to predict and follow progression of a wide range of diseases, such as metabolic disorders (e.g.. obesity, Type II diabetes, and NAFLD), neurodegenerative diseases (e.g. Alzheimer’s Disease and Parkinson’s Disease), and cancer (e.g. prostate cancer and breast cancer).