University of Massachusetts Chan Medical School

Contact Info:

Caroline Chidley

https://www.umassmed.edu/metabolomics/

Grants and Identifiers:

RRID: RRID:SCR_027036

Instrumentation:

Services Provided:

Relevant Publications:

1.) Munden AL, Mushtaq A, Lui DS, Edwards KM, Higgins DP, Biswas K, Walker RM, Crowley LH, Fanelli MJ, Ngyuen TK, Ericsson M, Godbole AA, Haley JA, Lewis CA, Spinelli JB, Harrison B, Raftery D, Djukovic D, Promislow DE, Miller DL, Walker AK (2025 Dec 1). Distinct S-adenosylmethionine synthases link phosphatidylcholine to mitochondrial function and stress survival PLOS Biology, 23(12), e3003075. . PMCID: 12680360.

Description:

Core offers the ability to perform both targeted (including stable isotope tracing studies) and untargeted metabolomics and lipidomics experiments using liquid- and gas-chromatography mass spectrometry (LCMS/MS and GCMS) on a fee-for-service basis. Offers expertise to assist with every stage of the metabolomics/ lipidomics experimental pipeline, including experimental design, method development, data acquisition and processing, data analysis and interpretation. Offers training on data analysis software including both open-source and vendor proprietary analysis software. Offers access to specialized equipment required for metabolomics/ lipidomics sample extraction and preparation, including a Cryomill and Bead Beater for homogenization of tumors, tissue, stool and whole organisms, and a liquid-handling robot for large scale plasma extractions.