NYU Langone’s Advanced Rodent Transgenics Laboratory (ART-Lab) is a resource for researchers who want to apply advanced molecular genetic techniques in rodent models of physiology and disease. Our lab is experienced at generating novel mutant and transgenic mouse strains using genome engineering in mouse embryos and in embryonic stem cells (ESCs).

Our lab scientists customize technologies to meet individual project needs. Available technologies include:
Generation of genome-edited mice by embryo pronuclear microinjection of DNA and genome editors (e.g., CRISPR/Cas9, site-specific recombinases) or traditional BAC transgenesis.
Generation of genome-edited mice from mouse embryonic stem cells (mESCs) by chimeric blastocyst injection.
Generation of genome-edited mice from mESCs by tetraploid blastocyst injection.
Gene targeting in mESCs using electroporation, including Knock-in into the Rosa26 and other safe harbor loci.
Generation of mice from induced pluripotent stem cells.
Assisted reproductive technologies.
Sperm and embryo cryopreservation, storage and import/export.
in vitro fertilization (IVF)
Embryo rederivation technologies for animal import into barrier vivaria through quarantine.

The Population Health Data Hub is an innovative and centralized resource to improve access, efficiency, and support for research teams working with a wide range of data sources to study and address population health issues. We are part of a rapidly growing “data ecosystem” of research data hubs and related services at NYULH.

Our goal is to help Population Health PIs and Analysts solve their administrative and analysis issues. This includes data acquisition, storage, cleaning, analysis, and dissemination.

NYU Langone’s Environmental Exposure and Analytical Chemistry Laboratory is a state-of-the-art facility designed for trace-level analysis of anthropogenic organic chemicals in environmental and biological specimens, offering services to our investigators and the greater scientific community. We specialize in mass spectrometry–based analysis, including targeted and nontargeted methods.The laboratory is capable of quantifying nearly all the organic analytes monitored by the Centers for Disease Control and Prevention (CDC) in the National Health and Nutrition Examination Survey (NHANES) program. Commonly assayed targets include phthalates, bisphenols, per- and polyfluoroalkyl substances (PFAS), glyphosate, organophosphate flame retardants, organophosphate pesticides, and other compound classes at biologically and environmentally relevant concentrations. Our nontargeted analysis workflows are capable of detecting hundreds to thousands of chemical features in a single sample, enabling the identification of unknown organic compounds without a priori target selection.Strong evidence shows that exposures from plastics, pesticides, and other anthropogenic chemicals disrupt endocrine regulation, with health effects extending from early development through adulthood. Building on research led by Prof. Leonardo Trasande and the NYU Center for Investigation of Environmental Hazards, which demonstrated that these exposures contribute to substantial disease burdens, premature mortality, and billions of dollars in healthcare costs, our laboratory operates as a shared resource within NYU Langone's Division of Advanced Research Technologies (DART), which is part of the Office of Science and Research (OSR). We provide precise chemical analysis to support studies on environmental exposures and their health impacts.

The Research Software Engineering (RSE) Core is a resource launched by NYU Langone, based in the Information Technology department in close collaboration with the NYU Grossman School of Medicine. We design, develop, optimize, and customize software to accelerate research.