primary_duns:
824771034
Elm & Carlton Streets
Buffalo, NY 14263-0001
United Stateshttps://www.roswellpark.org/shared-resources/biorepository-laboratory-servicescite this facility
Annmarie Nowak
The Biorepository & Laboratory Services Shared Resource (BLS) is a comprehensive data and biospecimen bank (malignant and normal tissue and their derivatives, blood and bone marrow) for research along with a range of services that accompany biospecimens. The overall mission of BLS is to facilitate access to human tissue, blood and bone marrow for investigators with Institutional Review Board (IRB) approved protocols emphasizing translational research. BLS plays an essential role at Roswell Park, helping investigators to establish Biospecimen and Data Research (BDR) protocols and supporting the submission of grants by providing feasibility analysis, cost estimates and letters of support.
is_active:
Yesbudget_end:
04/30/2026date_added:
08/02/2025agency_code:
NIHfiscal_year:
2025project_num:
5P30CA016056-48award_amount:
$4,468,904.00budget_start:
05/01/2025org_name:
ROSWELL PARK CANCER INSTITUTE CORPorg_state:
NYorg_country:
UNITED STATESorg_zipcode:
142630001primary_duns:
824771034abstract_text:
Roswell Park Comprehensive Cancer Center (Roswell Park), established in 1898 is one of a small number of freestanding, NCI-designated, comprehensive cancer centers and the only comprehensive center in New York State (NYS) outside of Manhattan. The sole mission of the Center is to eliminate cancer's grip on humanity through cancer research, treatment, prevention and education. The Cancer Center which is in its 46th year of funding, is currently organized around 4 research programs, 9 shared resources, a clinical trial infrastructure that prioritizes investigator-initiated and innovative clinical trials that are a product of the research programs and a community outreach and engagement (COE), Cancer Research Training & Education Coordination (CRTEC) that are interactive, cross-functioning and responsive to our catchment area. The Cancer Center supports 145 members and has recruited 162 new faculty since the previous review with 42 of them new members of the CCSG. Our cancer-relevant direct grant funding is currently $79M with 49% ($39M) coming from the NCI, a more than doubling of our NCI funding from 2018 with over 56% of funding in program/multi-PI type grants that underscores our commitment to collaborative research. Our high impact papers have increased to 29% from 10% in 2018 resulting in practice, paradigm and policy changing research. We have increased our focus on our community outreach and engagement, and we have an enhanced approach to our community and catchment area needs. The Specific Aims over the next 5 years are as follows: Aim 1: Innovation: To be a leader in the development of innovative approaches in cancer research across basic, clinical and population sciences to improve the quality of care for our patients in our catchment area and beyond. Aim 2: Translation: To enhance collaborative efforts between basic, clinical and population scientists toward the more effective translation of our discoveries into paradigm changing patient practices and interventions and policies. Aim 3: Education: To train and develop the next generation of scientists and physicians through innovative oncology-focused programs that continue to develop translational opportunities across the clinic, the basic science and population science areas. Aim 4: Community: To ensure that the needs and priorities of communities in our catchment area are catalyzing high- impact science with a specific focus on strategies drive rapid translation of scientific advances to reduce the cancer burden in our catchment area and beyond. Aim 5: To promote a culture of fairness, accountability, integrity and respect across our cancer center employees, scientists, physicians, nurses and healthcare staff, students and trainees and leadership toward a more productive workplace and to serve our community more effectively. Roswell Park continues to play a primary role in discovery and innovation in basic science findings that enable us to deliver the best cancer care to our patients in New York State, around the country and around the world.project_title:
Roswell Park Cancer Center Support Grantcontact_pi_name:
JOHNSON, CANDACE Stotal_cost:
$4,468,904.00is_active:
Yesbudget_end:
05/31/2029date_added:
09/21/2024agency_code:
NIHfiscal_year:
2024project_num:
1C06OD037775-01award_amount:
$7,731,872.00budget_start:
09/18/2024org_name:
ROSWELL PARK CANCER INSTITUTE CORPorg_state:
NYorg_country:
UNITED STATESorg_zipcode:
142630001primary_duns:
824771034abstract_text:
PROJECT SUMMARY/ABSTRACT. As a Comprehensive Cancer Center with a mission to `understand, prevent and cure cancer', Roswell Park has long recognized the value of human biospecimens linked with clinical and outcomes data for driving research discoveries. As such, the institute has supported the collection and banking of remnant tumor tissue from surgical procedures in the Pathology Network Shared Resource (PNSR) and the collection and storage of peripheral blood samples in the Hematologic Procurement Shared Resource (HPSR) and the DataBank and BioRepository (DBBR). Furthermore, samples from specific research initiatives, including large multi-institutional team science grants, have also been banked for research use. Unfortunately, these efforts have all arisen independently of each other with no coordinated vision or standardized operating procedures, resulting in scores of -80 and liquid nitrogen (LN2) freezers spread across the Roswell Park campus. The haphazard and fragmented growth of these resources and the fact that some of these collections have inventories that cannot be electronically queried by the Roswell Park research community has made access to these samples difficult and has delayed advances in biomedical research. Importantly, with some epidemiological studies including thousands of participants with multiple aliquots of blood components for each, retrieval of samples for analysis is an extremely laborious and time-consuming process, and keeping freezer doors opened for long periods of time to retrieve samples jeopardizes sample integrity. Here we propose to consolidate sample procurement, processing and banking for the three existing shared resources (PNSR, HPSR, and DBBR) and external studies into ONE Biorepository – a comprehensive and unified biobanking system with accompanying services at Roswell Park. We will also construct a state-of- the-art biospecimen storage facility on the first floor of GBSB, centered around acquisition of a Hamilton BiOS M6, an ultra-low temperature automated storage system with robotic sample handling and retrieval, such that freezer doors are never opened, thereby maintaining the highest levels of biospecimen integrity during storage, tracking and accession. ONE Biorepository will be accompanied by a renovated laboratory space that can accommodate the operational needs of all three preexisting biobanks and their research services. The newly renovated Biorepository and laboratory facilities enable streamlined and efficient practices for the processing, banking and use of human samples to advance biomedical research, at Roswell and with our regional and national NIH-funded partners.project_title:
ONE Biorepository: Comprehensive Integrated Biobanking Systemscontact_pi_name:
AMBROSONE, CHRISTINE B.total_cost:
$7,731,872.00Services are offerred outside of
Consulting is not offerred outside of Roswell Park Comprehensive Cancer Center
Last Updated: 04/30/2026
