The CoreMarketplace: MPI-CBG Light Microscopy Facility

Max Placnk Institute of Molecular Cell Biology and Genetics

Pfotenhauerstr. 108

Dresden,

01307

Germany

+49 351 210 2345

https://www.mpi-cbg.de/research/scientific-cores-support/scientific-services/light-microscopy/services

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Quicklinks:

https://www.coremarketplace.org/MPI-CBG_LMF https://www.coremarketplace.org/RRID:SCR_023307

Facility LIMS Page

PPMS Stratocore

Primary Contacts:

Jan Peychl

+49 351 210 2502

Britta Schroth-Diez

Facility RRID

RRID:SCR_023307

Facility Details

The mission of the MPI-CBG Light Microscopy Facility (MPI-CBG LMF) is to provide 24/7 access to state-of-the-art light microscopy techniques and instruments as well as to follow future trends. We assist through consultation, training, and project collaborations.

The LMF advises users during design and execution of their imaging projects. We provide support with selecting the most suitable imaging techniques, microscope systems, and setting up imaging experiments.

We offer our expertise in imaging techniques, such as

Spinning disk confocal microscopy
Laser scanning confocal microscopy
2-photon microscopy
Light sheet microscopy
Wide-field microscopy
Total internal reflection fluorescence (TIRF) microscopy
Laser capture microdissection
Extended resolution microscopy
Quantitative phase imaging
Live cell and organoid imaging
Photomanipulation

Furthermore, the LMF is constantly exploring new commercial technologies that can support the research mission of the MPI-CBG. We are also involved in multiple outreach and educational activities in Dresden, Germany and beyond.

Facility Policies

Services are offerred outside of

Consulting is offerred outside of Max Planck Institute of Molecular Cell Biology and Genetics

Last Updated: 05/19/2025

Services offered:

Facility Equipment

Olympus FluoView 300 Confocal Microscope

Confocal microscopy can improve conventional fluorescence images by recording fluorescence generated from the focal plane within the sample, while rejecting all other light coming from above or below the focal plane. The efficient point-scan/pinhole-detection confocal optics of the FluoView systems virtually eliminate out of focus light to produce high-contrast images with superb resolution. The FluoView systems are fully integrated workstations that incorporate user-friendly image acquisition and image analysis software with high-resolution confocal optics that require no user alignment. An , Windows-based graphic user interface allows new users to quickly generate images in various scan modes, such as XY, XZ, XT, XYZ, XYT, and XYZT. Standard image formats, including TIFF and AVI, permit easy, direct export of FluoView images to off-line analysis packages. XY scanning is performed with a pair of galvanometric mirrors, yielding a wide scanning range to cover up to a field number of 20. The optical zoom (up to 10x magnification) can be performed by narrowing the scanning range while maintaining the maximum pixel resolution of up to 2048 x 2048 pixels. [Product Link]

RRID:SCR_020339

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Zeiss Axio Vert series Axiovert 200 inverted microscope

Inverted microscope that is used for the examination of cell and tissue culture of sediments in culture flasks, Petri dishes, microtiter plates, etc. in transmitted and reflected light. It hass attachment possibilities for various tools (micromanipulation), different light sources, temperature control devices. [Product Link]

RRID:SCR_020915

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Zeiss Lightsheet Z.1 Lightsheet Fluorescence Microscope

Light sheet fluorescence microscope for the imaging of large cleared specimens. Lightsheet Z.1 with Clr Plan-Apochromat 20x/1.0 Corr nd=1.38 is used to perform experiments with tissue cleared by Scale medium (Hama et al, Nat Neurosci. 2011), which has a refractive index of n=1.38. [Product Link]

RRID:SCR_020919

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Zeiss LSM 780 Confocal Laser Scanning Microscope

Laser Scanning Microscopes (LSM) for high resolution imaging of biological or material samples. The compact scanning module can be fitted to an inverted (Axio Observer.Z1 RP or SP) or upright (Axio Imager.Z2, Axio Imager.M2 or Axio Examiner) microscope. [Product Link]

RRID:SCR_020922

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Zeiss LSM 880 with Airyscan Confocal Laser Scanning Microscope

Fully enclosed laser scanning confocal imaging microscopefor heating and environmental control with media perfusion capabilities and CO2 control. It can be used for Live Cell Imaging, FRET and Anisotropy, FRAP and FLIP, FCS, Photoactivation/ -conversion. [Product Link]

RRID:SCR_020925

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Zeiss PALM MicroBeam PALM

PALM MicroBeam scanning electron microscope for isolating uncontaminated source material simple. [Product Link]

RRID:SCR_020929

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Zeiss LSM 700

inverted

No additional equipment has been listed

Publications

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Links

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https://www.coremarketplace.org/?FacilityID=1688
https://www.coremarketplace.org/RRID:SCR_023307

Institution

Institution ROR ID: https://ror.org/05b8d3w18

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Keywords:

USEDit, ABRF, light microscopy techniques, light microscopy instruments, light microscopy

Resource Type:

access service resource, core facility, service resource

Citation:

Max Planck Institute of Molecular Cell Biology and Genetics Light Microscopy Core Facility (RRID:SCR_023307)

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Dresden University of Technology Mass Cytometry Core FacilityRRID:SCR_027145

Services:

Resources:

Contact Info:

Claudia Peitzsch

https://tu-dresden.de/cmcb/technologie-plattform/facilities/mass-cytometry

RRID:

RRID:SCR_027145

Description:

Facility provides customized solutions for complex single cell profiling with up to 45 markers simultaneously. Offers full service and established workflows from panel design, antibody labelling and sample processing to high-dimensional data analysis. Offers expertise in antibody conjugation, sample staining, and data analysis.

This facility does not provide services outside its institution

This facility does not consult outside its institution

Last updated:

07/02/2025

Other Facilities at Max Planck Institute of Molecular Cell Biology and Genetics

Technology Development StudioRRID:SCR_017842

Services:

Cell Culture

Cell Imaging

Computational - Biostatistics

Confocal Microscopy

Data Analysis

Microscopy

Resources:

Contact Info:

Rico Barsacchi

Pfotenhauerstrasse 108

Dresden, 01307 - Germany

https://www.mpi-cbg.de/research/scientific-cores-support/scientific-services/technology-development-studio-tds/services

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RRID:

RRID:SCR_017842

Description:

The TDS offers high content screening services to both academia and industry. This involves developing assays, optimizing reagents, miniaturisation, performing the screen and validating hits.
Biological systems screened include cell lines (in 2D and 3D), primary cells, stem cells, worms and zebra fish.
All data are analyzed using open source software (CellProfiler and KNIME) and the pipelines are shared with the clients for their input and feedback. Courses are also offered how to use the software packages.
The facility does not retain any IP, but charges for the full cost of the service. Offers for screening service can be made upon request and grants can be submitted together with prospective clients.

This facility provides services outside its institution

This facility provides consulting outside its institution

Last updated:

10/11/2024

DNA Microarray Facility

Services:

Data Analysis

DNA Analysis

Microarray

Real-time qPCR

RNA analysis

RNA Integrity

Resources:

Contact Info:

Julia Jarrells

Pfotenhauerstr. 108

Dresden, 01307 - Germany

www.mpi-cbg.de

Google Maps Location

Description:

The Microarray Facility currently provides service for three different commercially available DNA microarray platforms: Agilent, Affymetrix and NimbleGen. The Agilent hybridization oven and microarray confocal laser scanner set-up of the Microarray Facility allows for analysis of other 1x3â€ glass slide array platforms, also. Such platforms include but are not limited to, GE Healthcare, Illumina, or custom printed arrays. Any type of microarray, e.g. protein, peptide, antibody, lipid, glycan, etc. can be processed in the Microarray Facility.

We have expertise in designing custom microarrays, for example DNA Microarrays with the Agilent database eArray. We offer full service of microarray experiments including sample quality control, experimental design, execution of the experiments, data analysis and data storage. For the validation of DNA microarray results, we are equipped and experienced with qPCR analysis.

Services:

Gene expression analysis (1 color and 2 color)
ChIP-on-chip analysis
Array-based comparative genomic hybridization
miRNA expression analysis
Array-based and solution-based targeted
enrichment for Next Generation Sequencing
Any type of array processing, e.g. protein,
peptide, antibody, lipid, glycan, etc.
Validation of DNA microarray results with qPCR
Custom array design, e.g. with eArray tool

Expertise:

Comprehensive microarray proficiency
Professional support, teaching, and training
High throughput screening and large-scale data
analysis
Experimental design and assay development
Design and analysis of custom microarrays, such
as DNA, protein, peptide, antibody, lipid, glycan

Equipment:

Agilent microarray confocal laser scanner
Agilent hybridization oven
Agilent Bioanalyzer
NimbleGen hybridization system 4
Stratagene Mx 3000 P qPCR machines
Large-scale data analysis platform: GeneSpring

This facility provides services outside its institution

This facility does not consult outside its institution

Last updated:

03/02/2012

MPI-CBG Light Microscopy Facility (Microscopy (Electron, Fluorescence, Optical))

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Facility LIMS Page

Primary Contacts:

Facility RRID

Facility Details

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Facility Equipment

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Metadata

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Facility Profile QR Code (links to this profile)

(To see more facility information, click the in the upper right)

Filter Results. Click/Unclick items to select.

Dresden University of Technology Mass Cytometry Core FacilityRRID:SCR_027145

(To see more facility information, click the in the upper right)

Other Facilities at Max Planck Institute of Molecular Cell Biology and Genetics

Technology Development StudioRRID:SCR_017842

DNA Microarray Facility

(To see more facility information, click the in the upper right)

Contact Jan Peychl/Britta Schroth-Diez

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MPI-CBG Light Microscopy Facility

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