Provides support to experiments that use mouse models to elucidate mechanisms of normal physiology and disease processes, and to develop and test novel agents and therapies to treat diseases. Provides centralized facililty for breeding, genotyping, maintaining colonies, conducting animal experiments, collecting tissues, analyzing experimental results, and training personnel in proper procedures for conducting animal experiments. Core also hosts germ-free mouse facility that works with PI's to produce, distribute, and conduct experiments in germ-free and gnotobiotic mouse models. MEF/GCF offers expertise with genetic, induced, or orthotopic models of disease and coordinates with other USC Cores with respect tissue processing and preparation for various types of analyses.

Core offers resources and solutions for conducting genomics, transcriptomics, epigenomics and functional genomics projects. We work with researchers to determine project goals and design custom solutions. We assist at all stages of the project, from support in grant development to generation of publication-quality data. Services include Consultations,
Bioinformatics, Nucleic Acids purification, quantification and QC DNA Sequencing (SANGER and NGS), Library Constructions for NGS applications,Microarray Hybridization, Real Time PCR, Custom epigenomics applications, Lentiviral vectors and lentiviruses construction and production, CRIPR-CAS9sgRNAs and RNAi/shRNAs knockdown of individual genes and functional screening of sgRNA and shRNA libraries for target identification.

Electron Microscopy Center at USC is core facility providing all levels of technical support and consultation in area of light microscopy, electron microscopy, and elemental analysis. Provides microscopy and specimen preparation services for biological and materials science research. Offers training and access to all microscopes and ancillary equipmen.