The Center for Educational Technologies offers services to researchers looking for collaborators or contractors for their educational or training projects. We offer development tools and hosting services to educators creating their own online training resources.

The Laboratory for Synthetic-Biologic Interactions (LSBI) is a research facility housed in the Department of Chemistry. The LSBI is designed to be a multi-user laboratory supporting major research initiatives within the Chemistry Department, the university and extending to the broader academic and industrial scientific communities. Fifteen instruments are currently available on a fee-for-use basis, and others may be made available on case-by-case considerations.

The Texas A&M Preclinical Phenotyping Core provides a multitude of services on broad post-genomic assays for biochemical, preclinical, rodent phenotyping, and environmental toxicant studies.

The Microscopy and Imaging Center is a core user facility supported by the Office of the Vice President for Research. The MIC is staffed by research scientists with expertise in Transmission Electron Microscopy, Scanning Electron Microscopy, Light Microscopy, and supporting instruments therein. These staff members are happy to provide quality training and education through one-on-one sessions, short courses, formal courses, open house seminars, and more.

The Flow Cytometry Shared Resource Facility at Texas A&M mission is to provide the highest quality flow cytometry experimental design, data collection, data analysis and cell sorting services for the faculty, students and staff of the Texas A&M University system and surrounding universities and companies. We currently provide training for flow cytometers, imaging flow cytometer, and data analysis using IDEAS and FlowJo software. We also provide staff-assisted flow cytometry and imaging flow cytometry data acquisition, cell sorting, and data analysis. The core provides experimental design and consultation services. We also welcome and encourage collaborations on research projects. The FCF currently has a Beckman Coulter Moflo Astrios cell sorter, a Luminex/Amnis Image Stream X Mark II, a Luminex/Amnis Cell Stream, and a Becton Dickinson Accuri C6 flow cytometer. The Astrios cell sorter is housed in the ClassII BSC and has 3 lasers (405nm, 488nm, 642nm) and 11 detectors and can sort up to 6 populations simultaneously. The Image Stream X Mark II is equipped with 20x, 40x, 60x objectives, 4 lasers (405nm, 488nm, 561nm, 642nm), 10 detection channels, EV mode for small particle detection, and an autosampler. The Cell Stream is equipped with 3 lasers (405nm, 488nm, 642nm), 13 detection channels, EV mode for small particle detection, and an autosampler. The Accuri C6 is equipped with 2 lasers (488nm, 642nm), and 4 detection channels. The FCF also has two data analysis computer workstations equipped with IDEAS and FlowJo analysis software.

The AggieFab Nanofabrication Facility is a shared nano/microfabrication facility located on the 1st floor of the Frederick E. Giesecke Engineering Research Building at Texas A&M University. The facility has over 6,500 sq. ft. of class 100/1000 cleanroom space with a raised access floor and vertical laminar flow. There is an additional 4,500 sq. ft. of support space, totaling 11,000 sq. ft. AggieFab houses state-of-the-art equipment for a wide range of micro- and nanoscale fabrication of diverse materials. In addition to the purchase of new nanofabrication tools, the facility acquired $5 M nanopatterning and deposition equipment through a donation from Hewlett Packard Enterprise (HPE). These include a Zeiss Orion Helium Ion Microscope/Nanofab, FEI Helios DualBeam Focused Ion Beam (FIB), ASM Atomic Layer Deposition (ALD) tool, and a Clustex Multi-target deposition tool. The facility also has recently received $1.5 M from the Texas A&M University Research Development Fund to purchase an Oxford Estrelas DRIE tool and Heidelberg MLA150 Maskless Lithography tool to provide advanced substrate development capabilities. The main supporters of the facility are the Department of Electrical and Computer Engineering, TEES, and the Office of the Vice President for Research.

Provides histology (including cryosectioning, IHC and IFC) digital pathology and veterinary pathology (board certified veterinary pathologist on staff) services

We provide advanced imaging technologies and image analysis tools for a broad range of life sciences research. This includes vital imaging of cellular processes within cells, tissue explants, and organoids. A variety of support services for transmission electron microscopy of biological samples are available.

The primary goal of the AgriGenomics Lab (AGL) is to assist graduate students, staff and faculty launch, economize and expedite their research, especially when it involves DNA extraction and quality checks, targeted genotyping and DNA content analysis. We also will, as needed, facilitate usage of complementary cores and assist with research planning and data analysis.

AGL members have free lab access and reduced costs for services as well as one-on-one training and advising with AGL staff. TAMU system users can purchase services at a cost-effective rates. This service is especially useful for investigators interested in exploring new techniques, and obtaining pilot data sets for external funding proposals. Non-system members are also welcome to set up projects using AGL facilities.

The new Soft Matter Facility (SoMF) is the user facility focused on characterization of multifunctional soft materials. The facility includes four instrumentation suites based on the soft-matter-centered research areas which will be unified by the general theme of characterization of hierarchically structured multi-component, multifunctional soft materials: Molecular Characterization, Processing & Mechanics, Thin Films & Interfacial Analysis, and Nanostructure Characterization.

The Materials Characterization Facility (MCF) at Texas A&M University is a core user facility supported by the Office of the Vice President for Research, the College of Engineering/TEES and the College of Science. The MCF provides researchers in the TAMU community with access to high-end instrumentation essential for fundamental studies of the surface and interfacial properties of materials, such as ion and electron based spectroscopies, electron, optical and scanning probe microscopies. The MCF is staffed by research scientists with expertise in these areas, and they provide fundamental research training to students and faculty on our instrumentation as well as consolation of measurements needs and data interpretation. Beyond TAMU, the MCF also supports collaborative research projects with outside industrial users. Beyond research training, the facility also supports educational activities involving lab tours, workshops, hands on demonstrations, outreach and broader impact related activities through our open house and lunchtime seminar series.

The Protein Chemistry Laboratory performs a wide array of protein analyses including protein/peptide separations and characterization and proteomics analysis. Our major techniques are Amino Acid Analysis, Automated Edman Protein Sequencing, Electrophoresis and Chromatography-based protein/peptide separations and mass spectrometry. In addition, we have expertise and instrumentation for 2D Differential Gel Electrophoresis (2D-DIGE) analysis for high throughput protein expression profiling. We possess Shimadzu/Kratos Axima CFR MALDI-TOF and a Thermo Finnigan LCQ DecaXP Ion Trap mass spectrometers for protein/peptide mass measurement and protein ID from 1D and 2D gels. Our services are available to the entire Texas A&M System as well as outside academic and commercial clients.

The Protein Production, Characterization and Molecular Interaction (PPCMI) core provides cloning, expression and purification services of functional proteins at a scale that meets the quantity and purity benchmarks for structural, biophysical, biochemical, and therapeutics studies; it also characterizes macromolecular biophysics and interaction energetics using a wide variety of state-of-the-art instrumentation and techniques that can analyze association and kinetic binding constants by surface plasmon resonance, enthalpies and entropies of binding by isothermal titration calorimetry, as well as determination of stoichiometry, stability, and homogeneity by both techniques.

The IBT Flow Cytometry and Cell Sorting Facility (FCCSF) provides a wide array of cutting-edge flow cytometry and cell sorting services, along with the necessary scientific expertise to integrate this technology into your research projects.

In 2020, The High Throughput Flow Cytometry Program (HtFCP) received funding from CPRIT, in conjunction with the existing Combinatorial Drug Discovery Program (CDDP), both integral components of the Gulf Coast Consortia network. This partnership provides academic and commercial users with unprecedented access to the only High Throughput Flow Cytometry automated platform in Texas Medical Center. The HtFCP and High Throughput Research Screening Core CDDP now call the state-of-the-art TMC3 Helix Park Collaborative Building, their home, located at 7255 Helix Park, Houston, TX 77030.

The Microphysiological Leads Optimization and Toxicity Screening facility (MLOTS) supports lead optimization programs and has established a roster of medium-throughput microphysiologic screening platforms including tissue- and tumor-on-a-chip platforms, organoid, and spheroid culture systems that will be used to evaluate the efficacy and toxicity of new lead compounds and drug combinations.

The pharmaceutical industry has recognized the importance of implementing a “fail early” screening strategy early in the drug development process by adopting advanced physiological screening platforms and predictive in vitro toxicology testing. MLOTS supports a "fail early" approach as a lead optimization strategy by providing the resources to identify. toxic liabilities in lead series molecules before entering pre-clinical or clinical testing. MLOTS can evaluate NME for cardiovascular, neuro, or liver toxicity relative to reference standards using in vitro screening platforms.

The Combinatorial Drug Discovery Program (CDDP) resides in the Texas A&M Health Science Center’s Institute of Biosciences and Technology, Houston, TX. This core provides industry standard high throughput screening and automated microscopy capabilities to scientists performing drug discovery research. The core provides many benefits, such as access to an automated infrastructure that is capable of supporting both both phenotypic and biochemical targets. The CDDP provides ready access to collections of current FDA-approved drugs and clinical candidates exhibiting the ‘drug-like’ qualities of acceptable solubility, desirable ADME/toxicology properties and adequate bioavailability. These properties are important for rapid advancement of new agents into successful preclinical and clinical trials by discovering new therapeutic vulnerabilities alone or in combinations. The CDDP also has collections of mechanistically annotated informer sets that are pathway specific modulators for studying mechanism of action or target identification. The core also has collections of natural products and diverse sets of small molecules that can be interrogated for new target discovery. The greatest benefit of the core; however, is its fulltime professional staff. The screening team is composed of highly experienced biologists, biochemists, pharmacologists and data scientists with both pharmaceutical industry and academic experience. Each project is individually evaluated and a team of scientists from the CDDP is created to fit the specific needs of the project from assay design and development through primary, secondary and orthogonal screening. The team is committed to providing an integrated and highly collaborative program with every investigator.

The primary purpose of the IMIL is to support research progress and grant development by encouraging researchers to explore advanced imaging modalities and to incorporate them into their existing research programs.

The IMIL provides technical expertise and cutting-edge microscope systems to support the research of faculty and staff of Texas A&M University Health Science Center, Texas A&M University, and all other campuses. The IMIL includes six microscopy rooms, supporting facilities, and an image processing station.

Technical staff is available to train and assist with design, implementation, and analysis of experiments as well as assist in troubleshooting.