The mission of the Bioinformatics Data Science Core Facility is to provide scientific expertise and core infrastructure support in Bioinformatics and Biological Data Science for the Delaware research and education community. Drawing on the combined resources of the Center for Bioinformatics and Computational Biology (CBCB), the Delaware Biotechnology Institute (DBI), the Data Science Institute (DSI), and the Protein Information Resource (PIR), the Core provides both computing infrastructure and knowledgeable personnel with significant hardware, software and professional support for bioinformatics and computational needs. Staff scientists with broad expertise encompassing various areas of bioinformatics, computational biology, and biomedical data sciences provide services, consulting, and research collaborations. BioIT and HPC support is provided by the Computing Systems Manager and IT associates of the Delaware Biotechnology Institute.

CHRC is focused on supporting researchers with participant recruitment, both on a small and large scale. The center is aimed at ensuring participant recruitment reflects the population and community we serve, and improving awareness of University of Delaware research across Delaware and neighboring Maryland and Pennsylvania communities. CHRC coordinates research subject logistics such as screening, scheduling, transportation, and reimbursement. CHRC also provides the university community with data management education, database set-up, repository, maintenance, hardening and security. CHRC supports REDCap across UD and assists researchers in building and maintaining participant registries.

Facility houses NMR spectrometers and an EPR spectrometer in the Department of Chemistry and Biochemistry. These spectrometers are equipped with various probes and other key accessories for general and specialized applications.

The Flow Cytometry Core Facility, located at the University of Delaware STAR campus (UD) in Newark, Delaware, provides a wide variety of flow cytometry and single cell genomics services for internal and external investigators. The Core facility is equipped with –
• FACSAria Fusion high-speed cell sorter (4Laser),
• CytoFLEX LX Flow Cytometer analyzer (4Laser),
• BD Rhapsody HT Express Cell Processing Unit,
• Chromium X (10X Genomics)
• PipSeq (Illumina)
• Countess FL3 cell counter,
• Thermo Shandon Cytospin 4 & Eppendorf centrifuges
• General Laboratory facilities for Mammalian Cell Culture and Sample preparation,
• Laminar flow BSL-2 biosafety cabinet, microscopes and centrifuges.

The University of Delaware Bio-Imaging Center is a multi-user microscopy facility that houses state-of-the-art microscopy equipment. Our mission is to maintain state-of-the-art microscopy instrumentation and skilled staff scientists to assist and train researchers on all aspects of microscopy, including experimental design, sample preparation, imaging on microscopes, image analysis, data interpretation, and publication.
With a special emphasis on life sciences and soft materials, we are able to address the broad imaging needs of the university, non-profit and industrial research community. The center is open to all academic researchers and industrial clients on a fee-for-service basis. The center is housed at the Delaware Biotechnology Institute in the Ammon Pinizzotto Biopharmaceutical Innovation Center at the University of Delaware.

Protein identifications; PTM analysis; quantitative proteomics (label-based and label-free).

Core oversees humane animal care, housing, veterinary oversight, and regulatory compliance for all vertebrate research and teaching facilities across campus, partnering with the Institutional Animal Care and Use Committee (IACUC).

The University of Delaware Sequencing and Genotyping Center (SGC) supports genomics research through our established expertise with state-of-the-art genomics technologies. Our core center is located in the Delaware Biotechnology Institute, which is an interdisciplinary research unit at the University of Delaware. The SGC provides assistance with experimental design, user training, sample and data analysis. Instrumentation housed in the SGC supports high-throughput, single-molecule, and Sanger sequencing technologies, as well as qualitative and quantitative analysis of nucleic acids.

The Center for Translational Cancer Research Core Facility is a multi-user facility, with equipment located in Wolf Hall and the Helen F. Graham Cancer Center. Available equipment include an ABI 7000 and 7300 Prism real-time PCR, IVIS Lumina System imager, and BD FACSCalibur, FACSAria II flow cytometers (located at Graham cancer Center) as well an AlphaImager gel documentation system and FluorchemQ chemi-Imager. The facility also has a Glomax Multi-modal plate reader that allows for measuring luminescence, fluorescence and absorbance and several equipment for sample preparation: microcentrifuges, scales, ph meter, spectrophotometer etc. Facilities are available to university researchers, their collaborators and industry on a fee-for-service basis.

Consulting and services in X-ray Photoelectron Spectroscopy (XPS, also called ESCA), Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS), Atomic Force Microscopy (AFM)

The Protein Production Core (PPC) Facility is a core laboratory that serves academic investigators in Delaware. The PPC is part of shared core facilities supported by the Center of Biomedical Research Excellence (COBRE) in Membrane Protein Production and Characterization at the University of Delaware. The PPC has modern instrumentation for large scale expression, purification and characterization of prokaryotic and eukaryotic proteins for investigators and researchers. The core supports the production of proteins in quantities suitable for structural studies (X-ray and NMR) and functional studies (biological or catalytic). The PPC also has state-of-the-art analytical ultracentrifuge for studying macromolecule interactions.