The Bioinformatics Core Facility in the Cancer Research Division at Peter Mac provides a range of services and know-how for data analysis, pipeline management, and artificial intelligence research and operations. The team of bioinformaticians and postdoctoral scientists at the core work alongside laboratory, clinical researchers and other bioinformaticians to contribute to their experimental design, grant applications and the analysis and publication of genomic and transcriptomic data. Data types analysed by the core include whole-genome and whole-exome sequencing, targeted re-sequencing, radiological images, RNA-sequencing, single-cell RNA sequencing, ChIP-sequencing, NanoString and various types of microarray data. The core also develops and maintains software infrastructure required for bioinformatics processing, including pipelines and cloud provision systems. The core is increasing its support in artificial intelligence research and deployment.

Core works with researchers, clinicians and other research technology platforms to establish the best possible approach for any genomics experiment. Offers expertise on variety of off-the-shelf sequencing products and implementation or customisation of new protocols to meet demands of cancer research.

Core provides media and buffer preparation, labware sterilising services, consumable provision, general wet laboratory support services.

Provides mouse genotyping service, from extraction of genomic DNA from tissue to reporting of genotypes. Offers Mycoplasma testing of any cell line and authentication of human cell lines.

Core offers specialised microinjection services for generating transgenic strains of fruit fly Drosophila melanogaster.

Core to perform novel discovery-based high throughput compound, CRISPR and RNAi screens at any scale in both 2D and 3D formats, using liquid handling instruments, automated high content imaging microscopes, live imaging systems and large reagent libraries.

Provides tools and expertise in bio image analysis, histology, and microscopy. Facility allows for the preparation, visualization, and quantification of biological samples at the cellular and sub cellular levels. Researchers can choose to utilize our instruments independently or collaborate with our skilled staff through our fee-for-service options.