The Structural Biology Core is a multi-user facility serving both the VCU campus and external research institutes. The core encompasses X-ray crystallography, Cryo-Electron Microscopy (Cryo-EM), and Nuclear Magnetic Resonance (NMR) facilities, and is also closely associated with the School of Pharmacy Molecular Modeling facility.

The Structural Biology Core provides access to state-of-the art equipment, offering researchers the capability to determine the 3D structure of macromolecules and macromolecular complexes. This yields a diverse array of information on their biological or physiological functions, and enables structure-based drug design, protein-ligand or DNA binding studies, testing mutational effects on target macromolecules, and finding the absolute stereochemistry of chiral compounds.

Additionally, the core offers training, technical support, and collaborative opportunities, which are crucial for structural biologists and other researchers studying the structure of biological macromolecules and other materials.

The Genomics Core facility in Richmond VA, maintains a significant portfolio of instrumentation to support advanced sample/library preparation, high-throughput sequencing, real-time PCR and analysis.