The Chromatography Center, located within the Department of Chemistry in Hahn Hall South (Room 1001), is a vital component of Virginia Tech‘s analytical research infrastructure. This facility is dedicated to providing state-of-the-art separation science capabilities for the university‘s diverse research community and external partners.
The primary mission of the Chromatography Center is to enable complete qualitative and quantitative analysis of components within complex sample matrices. Chromatography is the most popular and proven technology for separating mixtures, and this facility supports critical research across numerous fields, including:
Chemistry and Biochemistry
Biology and Medicine
Environmental Science and Toxicology
Food, Nutrition, and Pharmaceutical Development

The Center possesses the capability for the extraction, separation, detection, and quantification of organic and other complex mixtures from gas, solid, or liquid matrices.

The Chromatography Center operates as one of the four principal research instrumentation facilities within the Department of Chemistry‘s Analytical Services group.

The VT Chemistry NMR Facility houses seven state-of-the-art, high-field spectrometers (400–600 MHz) equipped with a full complement of probes—room-temperature, LN2-cooled cryoprobes, 10 mm polymer probes, diffusion probes, and solid-state MAS probes. We offer the full suite of 1D/2D solution NMR, diffusion (DOSY), and solid-state NMR across a broad range of nuclei.

Analytical research facility specializing in X-ray materials characterization techniques, sample preparation and data analysis.

Associated with Virginia Tech's Fralin Life Sciences Institute, this light microscopy research resource facility offers confocal, extended and super resolution, and lightsheet imaging options, as well as assistance and training for researchers. The FAIM also has educational resources available for light microscopy basics, and image processing and analysis.

The Genomics Sequencing Center (GSC) at Virginia Tech Fralin Institute is a dedicated multi-user resource for the development and application of state-of-the-art, Next-Generation Sequencing (NGS) technologies. GSC is a “one-stop shop” providing rapid, cost-effective, experimental design consultation, and genomic and functional-genomics services using Illumina’s NovaSeq, NextSeq and MiSeq systems. Quality control and quality assurance metrics are incorporated into each standard operating procedure to monitor performance of each service provided. Liquid handling robots and a custom Laboratory Information Management System (LIMS) increase throughput, efficiency and quality of the data generated and allow sample tracking in real time. We have the expertise and capacity to extend our support to research projects performed at any scale, in a very efficient and organized manner. In fact, GSC has supported over 700 individual PIs worldwide. We also provide our expertise and capabilities for grant applications to various funding agencies.

SERVICES OFFERED:

Next-Gen Sequencing Platforms:
NovaSeq
NextSeq
MiSeq
Thermo Ion S5

DNA Library Preps:
DNA-Seq
Nextera
Methy-Seq
Exome Capture
16S/18S/ITS Amplicon Sequencing
Metagenomic Sequencing

RNA Library Preps:
mRNA-Stranded-Seq
Small RNA-Seq
Total Stranded RNA-Seq
Ultra Low Input mRNA-Seq (10-100 cells)

Multiplexing large number of samples

qPCR services using SYBR Green and TagMan assays

Nucleic Acid QC:
Agilent BioAnalyzer and TapeStation
qPCR services of NGS libraries
Qubit

Sanger Sequencing Services

Targeted and untargeted metabolomics and proteomics resources