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All Facilities >> The Ohio State University >> The Ohio State University Molecular Biology and Genomics Core
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Wirat Pipatpongpinyo
RRID:SCR_028289Core provides integrated, end-to-end support for molecular biology and genomics research. Services include DNA/RNA extraction, sample quality control, genotyping, qPCR/ddPCR, and next-generation sequencing using Illumina and Oxford Nanopore platforms. In addition to laboratory services, MBGC offers consultation, experimental design guidance, troubleshooting, and training to support high-quality and reproducible research outcomes.
Services are offerred outside of
Consulting is offerred outside of The Ohio State University
Last Updated: 04/15/2026
Illumina RNA/DNA NGS Library Construction
Long Read Sequencing Utilizing Oxford Nanopore’s MinION Platform
Nucleic Acid Quantitation (TapeStation, Qubit)
Sequencing - Next Generation Sequencing (NGS)
Agilent 4200 Tapestation Genetic Analyzer
Benchtop genetic analyzer electrophoresis system for DNA and RNA sample quality control. It can be used for next generation sequencing or Biobank workflow. [Product Link]
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Applied Biosystems SeqStudio Genetic Analyzer
SeqStudio Genetic Analyzer is fluorescent dye labeled genetic analysis system using capillary electrophoresis technology. Enables both sequencing and fragment analysis applications without the need to switch polymer type or capillary array length. Allows to perform both sequencing and fragment analysis in single run. [Product Link]
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Bio Rad ChemiDoc MP Imaging System
Instrument for imaging and analyzing gels and western blots by Bio Rad. Designed to address multiplex fluorescent western blotting, chemiluminescence detection, general gel documentation applications, and stain-free technology imaging needs. [Product Link]
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Bio-Rad QX200 Droplet Digital PCR System
Droplet generator and reader that provides absolute quantification of target DNA or RNA molecules for EvaGreen or probe-based digital PCR applications. [Product Link]
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Eppendorf 5075 epMotion Automated Liquid Handling System
System provides precise, accurate alternative to time-consuming manual pipetting and liquid handling tasks. The combination of accelerated operational speed, new software & hardware features and an increased number of worktable positions make the systems best for and flexible laboratory use across a wide range of liquid handling applications. To ensure easy and consistent use, epMotion 5075 employs both Eppendorf's established epBlue software and an new software assistant concept. This supports the programming of applications and ensures that all users can use the system with only initial training. In addition, novel features such as a new CleanCap option, including UV light decontamination and a HEPA filter for purified air, offer new standards of decontamination and sample safety. This is supported even further by an optical sensor that checks labware, liquid levels and tip counts and type at the start of each cycle, hugely decreasing any risk of error during the run. [Product Link]
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Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
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Illumina NextSeq 1000 and NextSeq 2000 Sequencing Systems
Benchtop sequencers that allow you to explore new science across variety of current and emerging applications, with higher efficiency and fewer restraints. [Product Link]
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Labconco CentriVap Refrigerated Centrifugal Concentrator
Refrigerated centrifugal concentrator that concentrates heat sensitive samples using centrifugal force, vacuum, and controlled temperature. Concentrator has heater and refrigeration systems have temperature range of negative 4 C to 100 C. [Product Link]
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MinION
Portable, real time device for DNA and RNA sequencing, putting you in control of your sequence data. Portable DNA/RNA sequencing by Oxford Nanopore Technologies. [Product Link]
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Nanodrop 8000 Spectrophotometer
Microvolume UV Vis spectrophotometer for nucleic acid and protein quantification that can measure multiple samples using 1 to 2 uL of samples. It can analyze spectrum of 220nm to 750nm. [Product Link]
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Qiagen QIAcube DNA/RNA Protein Purification System
Protein purification system that performs fully automated purification of nucleic acids and proteins in molecular biology applications. [Product Link]
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Thermo Fisher Qubit 2.0 Fluorometer Qubit 2.0
Invitrogen Qubit Flex Fluorometer can selectively, accurately measure the concentration of up to 8 samples of DNA, RNA or protein simultaneously. Compared to single sample microvolume fluorometers, using the Qubit Flex Fluorometer for multiple samples reduces your time to data by up to 50%, with time savings beginning with batches of as few as 8 samples. Combining the one-of-a-kind Qubit Flex Fluorometer and optimized Invitrogen Qubit reagents and tube strips offers a complete solution for DNA, RNA and protein quantification. [Product Link]
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Thermo Scientific Nanodrop 1000 Spectrophotometer
The Thermo Scientific NanoDrop™ 1000 is a spectrophotometer that performs measuring of 1 ul samples with high accuracy and reproducibility. The full spectrum (220nm-750nm) spectrophotometer utilizes a patented sample retention technology that employs surface tension alone to hold the sample in place. This eliminates the need for cumbersome cuvettes and other sample containment devices and allows for clean up in seconds. In addition, the NanoDrop 1000 Spectrophotometer has the capability to measure highly concentrated samples without dilution (50X higher concentration than the samples measured by a standard cuvette spectrophotometer). [Product Link]
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https://www.coremarketplace.org/?FacilityID=5869Institution
Institution ROR ID: https://ror.org/00rs6vg23Keywords:
ABRF, molecular biology and genomics services, DNA/RNA extraction, sample quality control, genotyping, qPCR/ddPCR, next-generation sequencing,
Resource Type:
service resource, access service resource, core facility
Citation:
Ohio State University Molecular Biology and Genomics Core Facility (RRID:SCR_028289)
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Cell Sorting
Consultations
DNA Extraction
ELISA
ELISpot
Experimental Design
Flow Cytometry
Flow Cytometry Data Analysis
Flow Cytometry Training
Multi-color Flow Cytometry
Multiparameter Flow Cytometry Assays
Multiplex Assay
PBMC Cryopreservation
PBMC Isolation
Spectral Cell Sorting
Spectral Flow Cytometry
Flow Cytometry
David Rose
700 Childrens's Drive
RB1 Flow Cytometry Core W0030
Columbus, OH 43205 - United States
RRID:SCR_028319
The Flow Cytometry and immune Monitoring Core at Nationwide Children's Hospital provides instrumentation, training, and high-level scientific and technical expertise relating to conventional and spectral cytometry, cell sorting, small particle analysis, ELISA/ELISpot, PBMC processing and cryopreservation, and multiplex assays. We offer a wide variety of instrumentation for assisted and self-use.
This facility provides services outside its institution
This facility provides consulting outside its institution
04/28/2026
Computational - Application Development
Computational - Bioinformatics
DNA Analysis
Genomics
Microarray
Real-time qPCR
RNA analysis
RNA Integrity
Sequencing - DNA Sequencing
Sequencing - Next Generation Sequencing (NGS)
Vijay Nadella
700, Childrens Drive
W470, Biomedical Genomics Core, Nationwide Childrens Hospital
Columbus, OH 43205 - United States of America
RRID:SCR_017840
The Biomedical Genomics Core (BGC) is a nationally recognized provider of expertise in multiple aspects of genomics data generation and analysis. The services include consultation and assistance with experimental design, quality control of starting material (DNA or RNA), microarray and next-generation sequencing data generation, bioinformatics, statistical analysis and interpretation. The core is comprised of three units:
BGC Microarray Unit: In 2009, the BGC Microarray Unit was awarded with “Certified Service Provider†status by Agilent Technologies, the first academic laboratory in the US to have achieved this. This certification ensures that our clients receive superior microarray processing and data with regards to quality, reproducibility, and reliability. Specific services include custom array design, gene expression analysis for eukaryotes and prokaryotes, array comparative genomic hybridization (aCGH) to detect genomic aberrations and copy number variants (CNVs), splice variant analysis and comprehensive microRNA profiling of the entire miRNome.
BGC Sequencing Unit: We have over seven years of experience with next-generation sequencing data generation and analysis and we have been providing Sanger sequencing services for over ten years. The BGC Sequencing unit assists the investigators with multiple aspects of next-generation sequencing, including library preparation, sequence generation and data analysis. We provide advanced bioinformatics support to analyze the complex sequencing datasets generated on the next generation sequencing platforms. The core is equipped with Illumina HiSeq 2500 sequencing system which is capable of producing 600 billion base pairs (600 GB) of sequence data, enabling us to sequence 5 human genomes at 30X coverage in a single 14 day instrument run or 1 human genome in 40 hours utilizing RAPID Mode. For smaller genomes the core utilizes the Illumina MiSeq Personal Sequencer which has an 8.5 Gb output in under 40 hours. These technologies are being utilized for multiple applications including human genome re-sequencing studies for rare variant discovery and structural variation analysis (both targeted capture and whole genome), gene expression and transcriptome analysis (RNA-Seq and miRNA-Seq of both eukaryotes and prokaryotes), epigenomic studies including DNA-Protein interaction analysis (ChIP-Seq) and methylation analysis (Methyl-Seq), and de novo genome assembly of both bacterial and viral genomes. The BGC Sequencing unit is a certified service provider for SureSelect capture technology, a genome partitioning strategy that allows investigators to target their sequencing strategies to defined regions of the genome or the entire human exome. We also provide Sanger sequencing services for routine sequencing of plasmid and PCR templates through ABI 3130xL Genetic Analyzer.
BGC Bioinformatics Unit: The Bioinformatics Unit is comprised of a dynamic team of six computational biologists, with the substantial technical and bioinformatics expertise required to oversee the multiple platforms that acquire, store and analyze large and complex data sets generated by the BGC Microarray and Sequencing Units. Integration of this team within the BGC is critical to its success, ensuring that team members are able to learn new methodologies and develop novel analysis approaches in pace with the technological growth that has become a primary driving force for biological discovery. The bioinformatics unit provides services on a collaborative basis and serves as an interface between the research investigator and the multiple domains that are required to handle the size and complexity of genomic data. With our high performance compute cluster and 700TB of clustered high performance disk space we are able to support the analysis of both large and small scale sequencing projects. We are uniquely positioned to adapt and develop new computational tools in a manner that is driven by the demands of our research community as it utilizes new technologies. As a part of Dr. Peter White’s research group, BGC Bioinformatics Unit also focuses on the development of analytical pipelines for human genome resequencing, exome capture and the identification of disease causing genetic variants. The unit also evaluates and supports multiple software products for genomics applications that are designed to make data analysis tools accessible to biologists.
This facility provides services outside its institution
This facility provides consulting outside its institution
08/19/2014
Biorepository
Chris Manring
420 W 12th Ave
Room 326A
Columbus, OH 43240 - United States
RRID:SCR_023052
Human tissue biorepository offering procurement and distribution services for samples obtained from patients with hematologic malignancies
This facility provides services outside its institution
This facility provides consulting outside its institution
12/14/2022
Consultation
Data Analysis
DOSY NMR
Experimental Design
High And Low Temperature NMR
Macromolecule NMR
NMR Instrument Access
Nuclear Magnetic Resonance (NMR)
Polymer NMR
Protein NMR
Qualitative And Quantitative NMR Analysis
Sample Preparation
Small Molecule NMR
Solid State NMR
Training
Major Instrumentation
RRID:SCR_027162
Advanced high-field NMR facility combines many capabilities spanning solution and solid state NMR, high sensitivity cryoprobes, ultrafast spinning MAS probes, as well as Dynamic Nuclear Polarization.
This facility provides services outside its institution
This facility provides consulting outside its institution
05/22/2026
RRID:SCR_028429
Core provides technologies and expertise to accelerate discoveries in cancer immunology and immunotherapy. Offers advanced tools for immune profiling, spatial biology, and translational studies, enabling innovation that drives new therapies for patients.
This facility does not provide services outside its institution
This facility does not consult outside its institution
05/12/2026
3D &
4D Image Processing Stations
Analysis Workstations
Brightfield Microscopy
Cell Imaging
Confocal Microscopy
Confocal/ Super Resolution Microscope
Consultation
Consultations
Correlative Light Electron Microscopy
Cryo-Ultra Microtomy
Deconvolution
Differential Interference Contrast Microscopy
Electron Microscopy
Experimental Design
Fluorescence Microscope With Optical Sectioning Capability
Immuno Electron Microscopy
Live Cell Imaging
Microscopy
Microtomy/Electron
Microtomy/Light
Multiphoton Microscopy
Multiphoton/ Harmonic Generation Microscope
Phase Contrast Microscopy
Sample Preparation
Sputter Coating
Super-resolution Microscopy
TIRF Microscopy
Tissue Embed
Tissue Processing
Training
Transmission Electron Microscopy
Widefield Microscopy
Microscopy (Electron, Fluorescence, Optical)
Jeffrey Tonniges
460 W. 12th Ave.
Biomedical Research Tower 2nd floor
Columbus, OH 43210 - United States
RRID:SCR_025078
CMIF is a full-service facility, offering services from sample preparation to image processing. We offer a wide variety of instrumentation for use such as electron microscopy, light microscopy, and access to other instrumentation for use in sample prep.
This facility provides services outside its institution
This facility provides consulting outside its institution
05/06/2024
Analysis Workstations
Consultations
Cryo-Electron Microscopy
Data Analysis
Data Processing And Interpretation
Drug Discovery
Electron Microscopy
Focused Ion Beam (FIB)
MicroCT
Microscopy
Outreach
Sample Preparation
Scanning Electron Microscopy
Structural Biology
Transmission Electron Microscopy
X-ray Diffraction and Scattering
Microscopy (Electron, Fluorescence, Optical)
CEMAS
1305 Kinnear Road
Suite 100
Columbus, OH 43206 - United States of America
RRID:SCR_021294
CEMAS: the materials characterization hub for business and academia.
The Center for Electron Microscopy and Analysis (CEMAS) is a centralized, coordinated imaging facility where traditional boundaries between disciplines are eliminated.
With one of the largest concentrations of electron and ion beam analytical microscopy instruments in any North American institution, CEMAS brings together multidisciplinary expertise to drive synergy, amplify characterization capabilities, and challenge what is possible in analytical electron microscopy.
Our world-class multidisciplinary approach enables academic and business partners to "see more" than ever before.
We are challenging the current characterization limitations in medicine, environmental science, energy materials and beyond.
Our full-service facility - from extensive sample preparation laboratories to image-processing tools and support - allows researchers to carry out their entire microscopy and analysis program at CEMAS. Located in a custom designed facility on The Ohio State University's West Campus, every instrument in the facility meets or exceeds manufacturer performance specifications.
We have ambitious plans to expand the facility to include new instrumentation for which we are currently seeking funds, and to extend our capabilities further into soft and biological materials. We have designed the new environment with this in mind, and potentially have space to accommodate up to four aberration corrected instruments.
FEATURES OF CEMAS:
-Includes over $40M in equipment.
-Housed in a custom-designed environment.
-Every instrument in the facility is meeting or exceeding manufacturer performance specifications.
-One of the largest concentrations of electron and ion beam analytical microscopy instruments in any North American institution.
-Imaging and analytical facilities are complemented by extensive sample preparation facilities.
-Supported by passionate, highly skilled staff with expertise in all aspects of electron microscopy.
KEY SERVICES:
-World class multi scale imaging facility: optical scale to atomic scale.
-A unique, custom-designed environment where every instrument meets or exceeds manufacturer performance specifications.
-Highly skilled support staff available to all users.
-The electron microscopy collaboratory: a digital theater providing remote access allows students and lecturers to seamlessly operate electron and ion microscopes.
-Delivering solutions to medicine, advanced manufacturing, environmental science, energy harvesting and storage, and healthcare.
-Extensive sample preparation laboratories.
This facility provides services outside its institution
This facility provides consulting outside its institution
07/15/2022
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