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All Facilities >> University of Notre Dame >> Notre Dame Genomics & Bioinformatics Core Facility
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Melissa Stephens
The Genomics & Bioinformatics Core Facility (GBCF) at Notre Dame serves a diverse research community that spans basic biomedical research in human disease, vector disease research, population genomics, and environmental genomics. Utilizing Illumina sequencing, single-cell analysis, and spatial transcriptome analysis, we offer comprehensive solutions designed to acquire data for a broad range of applications including metagenomics, cancer genomics, microbial genomics, transcriptomics, and epigenomics for both model and non-model systems. Applying robust bioinformatics tools and biocomputing resources, we offer guidance and analysis workflows specifically tailored to your needs.
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Consulting is offerred outside of University of Notre Dame
Last Updated: 02/11/2025
10x Genomics Xenium Spatial Transcriptomics
ABI3730XL Sanger Sequencing And Fragment Analysis
BluePippin Automated Size Selection
Custom And Specialty NGS Workflows
High-intensity Acoustic Shearing
2100 Bioanalyzer Instrument
The 2100 Bioanalyzer system is an automated electrophoresis tool that provides precise analytical evaluation of various samples types in many workflows, including next generation sequencing (NGS), gene expression, biopharmaceutical, and gene editing research. Digital data is provided in a timely manner and delivers objective assessment of sizing, quantitation, integrity and purity from DNA, RNA, and proteins. Minimal sample volumes are required for an accurate result, and the data may be exported in a many different formats for ease-of-use. [Product Link]
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Agilent 4150 TapeStation System
This TapeStation System analyzes nucleic acids for up to 16 samples per run. [Product Link]
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Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
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Illumina NextSeq 1000 and NextSeq 2000 Sequencing Systems
Benchtop sequencers that allow you to explore new science across variety of current and emerging applications, with higher efficiency and fewer restraints. [Product Link]
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https://www.coremarketplace.org/?FacilityID=2874Institution
Institution ROR ID: https://ror.org/00mkhxb43Keywords:
ABRF, genomics experiments, bioinformatics analysis, next generation, Illumina sequencing, DNA and RNA library construction,
Resource Type:
access service resource, service resource, core facility
Citation:
Notre Dame Genomics and Bioinformatics Core Facility (RRID:SCR_025555)
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Analytical Ultracentrifugation+++Antibody Characterization+++Automated Liquid Handling+++Biological Mechanism+++Bioluminsecence Imaging+++Circular Dichroism (CD)+++Consultation+++Crystal Optimization+++Data Analysis And Interpretation+++Differential Scanning Fluorimetry (DSF)+++DNA Analysis+++Drug Discovery+++Experimental Design+++Fragment-based Drug Discovery+++Fragment-based Screening+++High-throughput Screening+++Image Aquisition+++Image Processing And Analysis+++Isothermal Titration Calorimetry (ITC)+++Molecular Imaging+++Monoclonal Antibody+++Phosphor Imaging+++Protein Crystallization+++Protein Extraction/Purification+++Protein Production+++Protocol Development+++Real-time qPCR+++RNA analysis+++Sample Preparation+++Shared Instrumentation Oversight & Maintenance+++Small Molecule Compound Screening+++Spectroscopy+++Structural Biology+++Surface Plasmon Resonance (SPR)+++Thermal Analysis+++Training+++X-Ray Crystallography
Biophysics
Giselle Jacobson
446C Stepan Chemistry Hall
Notre Dame, IN 46556 - United States
RRID:SCR_023867
Other CIDs:1S10OD028553-01
1S10OD036273-01
1S10OD038334-01
The Biophysics Instrumentation Core (BIC) Facility offers sophisticated instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for the isolation and purification of macromolecules for subsequent detailed biophysical analysis.
This facility provides services outside its institution
This facility provides consulting outside its institution
04/29/2026
Mass Spectrometry
RRID:SCR_025596
Core provides analysis of large and small molecules using several ionization methods, low or high resolution, hyphenated techniques, proteomics, and metabolomics.
This facility does not provide services outside its institution
This facility does not consult outside its institution
08/13/2024
Magnetic Resonance
RRID:SCR_025599
Core supports research in chemistry, biochemistry, molecular biology, engineering and related fields. The MRRC operates six solution-state NMR spectrometers (400 to 800 MHz), a solid-state 300 MHz NMR instrument, and an X-band EPR spectrometer. Most instruments are equipped with sample changers for increased sample throughput.
This facility does not provide services outside its institution
This facility does not consult outside its institution
08/13/2024
Transgenics
RRID:SCR_025588
Core develops and uses gene-targeting technology to investigate pathophysiological roles of genes of blood coagulation, anticoagulation, and fibrinolytic pathways in hemostasis, with associated relevance to embryonic development, cancer, infection, and inflammation.
This facility does not provide services outside its institution
This facility does not consult outside its institution
08/13/2024
Animal Facilities (Zebrafish, Fly, Mouse, Vivarium)
RRID:SCR_025552
Home to virtually all laboratory animals. Services include Procurement, Animal care, Breeding, Training,Limited procedures for research.
This facility does not provide services outside its institution
This facility does not consult outside its institution
08/13/2024
2D &
3D Illustration+++3D &
4D Image Processing Stations+++3D Visualization+++Analysis Workstations+++Animal Training +++Biochemical Analysis+++Biological Mechanism+++Biological photography/Photomicrography+++Body Composition+++Cell Imaging+++Clinical Imaging - Small Animal (luminescence/fluorescence)+++Clinical Imaging - Small Animal (X-ray, Ultrasound, microCAT, MRI)+++Computed Tomography (CT)+++Computer-assisted Neuron Tracing And Analysis+++Confocal Microscope With FCS/FLIM Capabilities +++Confocal Microscopy+++Confocal/ Super Resolution Microscope+++Consultation+++Consultations+++Correlative Light Electron Microscopy+++Cryostat Histology+++Customized Protocols+++Data Analysis+++Data Analysis And Interpretation+++Data Processing+++Data Processing And Interpretation+++Data Visualization+++Deconvolution+++Drug Discovery+++Electron Microscopy+++Fluorescence Lifetime+++Fluorescence Microscope With Optical Sectioning Capability+++Focused Ion Beam (FIB)+++Functional Brain Imaging+++H&
E Staining+++Hi
Imaging (Cell, Molecular, PET, Translational)
Sarah Chapman
340 McCourtney Hall
Notre Dame, IN 46556 - United States
RRID:SCR_022743
The NDIIF provides an integrated suite of sophisticated microscopes and imaging stations that enable expert users to address the most complex modern research problems and, equally important, expert staff, including technicians and research specialists, to guide the non-expert users. The facility offers imaging expertise in Electron Microscopy, Optical Microscopy, In Vivo Imaging, and Histology.
This facility provides services outside its institution
This facility provides consulting outside its institution
07/14/2023
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